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| 카탈로그 번호 | MY262012 |
|---|---|
| 설명 |
Recombinant Mouse IL3 Protein, N-His (MY262012) expressed in E. coli, spanning Asp33-Cys166. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | P01586 |
| 단백질 길이 | Asp33-Cys166 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 17.40 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Hematopoietic growth factor, IL-3, IL3, Interleukin-3, MCGF, Mast cell growth factor, Multipotential colony-stimulating factor, P-cell-stimulating factor |
| 배경 | Interleukin-3 is a ~18 kDa protein. Cytokine secreted predominantly by activated T-lymphocytes as well as mast cells and osteoblastic cells that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Also stimulates mature basophils, eosinophils, and monocytes to become functionally activated. In addition, plays an important role in neural cell proliferation and survival. Participates as well in bone homeostasis and inhibits osteoclast differentiation by preventing NF-kappa-B nuclear translocation and activation. Mechanistically, exerts its biological effects through a receptor composed of IL3RA subunit and a signal transducing subunit IL3RB. 1. Jaster, R. et al. (1999) Cellular signalling 11, 331-5. PMID: 10376805 2. Tong, Y. et al. (2020) JCI insight 5. PMID: 31990690 3. Silvennoinen, O. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 8429-33. PMID: 8378315 |
| 참고사항 | For research use only |
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