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| 카탈로그 번호 | MD462012 |
|---|---|
| 설명 |
Recombinant Mouse OR51E2 Protein, N-His (MD462012) expressed in E. coli. Purity: >90% by SDS-PAGE.
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q8VBV9 |
| 단백질 길이 | Ser2-Gly27&Ser75-Ala98&Lys163-Thr200&Tyr291-Thr320 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 예측 분자량 | 16.14 kDa |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | HPRAJ, OR51E2, Olfactory receptor 51E2, Olfactory receptor OR11-16, PSGR, Prostate-specific G-protein coupled receptor |
| 배경 | Olfactory receptor 51E2 is a ~35 kDa protein. Olfactory receptor. The activity of this receptor is probably mediated by G-proteins which induce elevation of intracellular Ca(2+), cAMP and activation of phosphorylation of the protein kinases PKA and MAPK3/MAPK1. Activation of OR51E2 may affect melanocyte proliferation, differentiation, and melanogenesis and may increase proliferation and migration of primary retinal pigment epithelial (RPE) cells. Activated by the short chain fatty acids (SCFA), acetate and propionate. In response to SCFA, may positively regulate renin secretion and increase blood pressure. 1. Pluznick, JL. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 4410-5. PMID: 23401498 2. Chang, AJ. et al. (2015) Nature 527, 240-4. PMID: 26560302 3. Torres-Torrelo, H. et al. (2018) Nature 561, E33-E40. PMID: 30258151 |
| 참고사항 | For research use only |
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