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| 카탈로그 번호 | MD634012 |
|---|---|
| 설명 |
Recombinant Mouse Serpinb1a Protein, N-His (MD634012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 발현 시스템 | E. coli |
| 등록번호 | Q9D154 |
| 단백질 길이 | Met1-Pro379 |
| 응용 분야 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 종 | Mus musculus (Mouse) |
| 성질 | Recombinant |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >90% as determined by SDS-PAGE. |
| 형태 | Lyophilized |
| 저장 완충액 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Leukocyte elastase inhibitor A, Serine protease inhibitor EIA, Serpin B1a, Serpinb1, Serpinb1a |
| 배경 | Leukocyte elastase inhibitor A is a ~42 kDa protein. Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also acts as a potent intracellular inhibitor of granzyme H. 1. Benarafa, C. et al. (2007) The Journal of experimental medicine 204, 1901-9. PMID: 17664292 2. Benarafa, C. et al. (2011) Journal of leukocyte biology 90, 21-9. PMID: 21248149 3. Benarafa, C. (2011) Methods in enzymology 499, 135-48. PMID: 21683252 4. Choi, YJ. et al. (2019) Nature immunology 20, 276-287. PMID: 30692621 5. Benarafa, C. et al. (2002) The Journal of biological chemistry 277, 42028-33. PMID: 12189154 6. El Ouaamari, A. et al. (2016) Cell metabolism 23, 194-205. PMID: 26701651 |
| 참고사항 | For research use only |
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