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| 카탈로그 번호 | VK689016 | ||||
|---|---|---|---|---|---|
| 설명 |
Anivovetmab (VK689016) is a research-grade recombinant antibody targeting Capsid protein VP2. Produced in mammalian cells with native-like glycosylation.
Highlights
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| 종 반응성 | Canine parvovirus type 2 (CPV2) | ||||
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| 숙주 종 | Canine | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2, kappa | ||||
| 발현 시스템 | Mammalian cells | ||||
| 타겟 | Capsid protein VP2 | ||||
| 내독소 수준 | < 10 EU/mg | ||||
| 순도 | >95% purity as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P61826 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 대체 이름 | KIND030, KIND-030, KIND030, 2370896-63-0 | ||||
| 배경 | Capsid protein VP2 is a ~64 kDa protein. Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 and VP2, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptor TFRC. This attachment induces virion internalization predominantly through clathrin-endocytosis. Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region and nuclear localization signal(s). | ||||
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anivovetmab
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
