Anti-Human Flt-3 Ligand/FLT3L Reference Antibody (AMG 329, RUO) (HW688026)

Name: Anti-Human Flt-3 Ligand/FLT3L Reference Antibody (AMG 329, RUO)
Brand: abinScience
SKU: HW688026
Price: 370 USD
Availability: InStock

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사양:

100ug
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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HW688026

설명

Research Grade Anti-FLT3 ligand Antibody (AMG 329) [AMG 329] (HW688026) is a human monoclonal antibody detecting Receptor-type tyrosine-protein kinase FLT3 in ELISA, Bioactivity: FACS, Functional assay, Research in vivo. Suitable for Human.

Highlights

●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

숙주 종

Human

클론성

Monoclonal

이소타입

IgG1, lambda

클론 ID

AMG 329

발현 시스템

Mammalian cells

성질

Recombinant

타겟

Receptor-type tyrosine-protein kinase FLT3, EC:2.7.10.1, FL cytokine receptor, Fetal liver kinase-2, FLK-2, Fms-like tyrosine kinase 3, FLT-3, Stem cell tyrosine kinase 1, STK-1, CD135, FLT3, CD135, FLK2, STK1

내독소 수준

< 10 EU/mg as determined by LAL method.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P36888

형태

Liquid

저장 완충액

0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

대체 이름

MEDI1116,VIB-1116, HZN-1116, VIB 1116, VIB1116, HZN 1116, HZN1116

배경

Receptor-type tyrosine-protein kinase FLT3 (FLT3 ligand) is a ~112 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B.

참고사항

For research use only. Not suitable for clinical or therapeutic use.

이미지

SDS-PAGE

SDS-PAGE for Research Grade Anti-FLT3 ligand Antibody (AMG 329)

참고 문헌

데이터시트

Anti-Human Flt-3 Ligand/FLT3L Reference Antibody (AMG 329, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human Flt-3 Ligand/FLT3L Reference Antibody (AMG 329, RUO) (HW688026)

개요

이미지

참고 문헌

데이터시트

SDS