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| 카탈로그 번호 | VK421266 |
|---|---|
| 종 반응성 | Human respiratory syncytial virus A (HRSV-A) |
| 응용 분야 | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG1 |
| 클론 ID | RSM01 |
| 생물학적 활성 | RSM-01 tightly binds to the highly conserved Ø site on the Pre-F protein, blocks viral conformational changes, inhibits viral fusion with host cell membranes, and prevents viral entry into cells. It exhibits ultra-high neutralizing activity against both RSV subtype A and subtype B [1]. |
| 타겟 | F, F1, F2, Fusion glycoprotein F0, Fusion glycoprotein F1, Fusion glycoprotein F2, Intervening segment, Pep27, Peptide 27, p27 |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P03420, P11209, 12568, O36634, P13843 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | RSM-01, RSM01, RSM01 |
| 배경 | Fusion glycoprotein F0 (Prefusion/Pre-F) is a ~63 kDa protein. Inactive precursor that is cleaved at two sites by a furin-like protease to give rise to the mature F1 and F2 fusion glycoproteins. |
| 참고 문헌 | 1. Scotta MC, et al. Current strategies and perspectives for active and passive immunization against Respiratory Syncytial Virus in childhood. J Pediatr (Rio J). 2023;99 Suppl 1(Suppl 1):S4-S11. [VK421266] |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-HRSV Prefusion/Pre-F Antibody (RSM01)
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