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| 카탈로그 번호 | HX902016 |
|---|---|
| 설명 |
Anti-Human CD202b/TEK/TIE-2 (UBX2050) (HX902016) is a research-grade recombinant antibody targeting CD202. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | UBX2050 |
| 발현 시스템 | Mammalian cells |
| 타겟 | VMCM, TIE2, Tunica interna endothelial cell kinase, CD202b, Tyrosine-protein kinase receptor TIE-2, TEK, Angiopoietin-1 receptor, VMCM1, Endothelial tyrosine kinase, Tyrosine-protein kinase receptor TEK, p140 TEK, Tyrosine kinase with Ig and EGF homology domains-2, hTIE2 |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | Q02763 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | UBX2050 |
| 배경 | Angiopoietin-1 receptor (CD202b/TEK) is a ~125 kDa protein. Tyrosine-protein kinase that acts as a cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of pro-inflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angiogenesis, depending on the context. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human CD202b/TEK/TIE-2 (UBX2050)
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