Anti-Human TLR3 Reference Antibody (CNTO-3157, RUO) (HT477016)

Name: Anti-Human TLR3 Reference Antibody (CNTO-3157, RUO)
Brand: abinScience
SKU: HT477016
Price: 326 USD
Availability: InStock

가격(USD):

사양:

수량:

문의하기

개요

카탈로그 번호	HT477016
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG
클론 ID	CNTO-3157
발현 시스템	Mammalian cells
타겟	TLR3, CD283, Toll-like receptor 3
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	O15455
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	CNTO-3157, CNTO3157, CNTO3157
배경	Toll-like receptor 3 (CD283/TLR3) is a ~103 kDa protein. Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
참고 문헌	1. Silkoff P E, et al. TLR3 Blockade in Rhinovirus-Induced Experimental Asthma Exacerbations[J]. [HT477016]
참고사항	For research use only. Not suitable for clinical or therapeutic use.