Anti-Human Transferrin R/TfR Reference Antibody (AOC 1001, RUO) (HY036046)

Name: Anti-Human Transferrin R/TfR Reference Antibody (AOC 1001, RUO)
Brand: abinScience
SKU: HY036046
Price: 326 USD
Availability: InStock

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사양:

100ug
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100mg

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HY036046

설명

Anti-Human CD71/TFRC (AOC 1001) (HY036046) is a research-grade recombinant antibody targeting CD71. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

종 반응성

Human

응용 분야

ELISA, Bioactivity: FCM, Functional assay, Research in vivo

숙주 종

Human

클론성

Monoclonal

이소타입

IgG

클론 ID

AOC 1001

발현 시스템

Mammalian cells

성질

Recombinant

타겟

CD71, T9, TFRC, TR, TfR, TfR1, Transferrin receptor 1, Transferrin receptor protein 1, Transferrin receptor protein 1, serum form, Trfr, p90, sTfR

내독소 수준

< 10 EU/mg as determined by LAL method.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P02786

형태

Liquid

저장 완충액

0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

대체 이름

AOC-1001, AOC1001, AOC1001

배경

Transferrin receptor protein 1 (CD71/TFRC) is a ~84 kDa protein. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. A second ligand, the hereditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

1. Senyilmaz, D. et al. (2015) Nature 525, 124-8. PMID: 26214738

2. Jabara, HH. et al. (2016) Nature genetics 48, 74-8. PMID: 26642240

참고사항

For research use only. Not suitable for clinical or therapeutic use.

이미지

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human CD71/TFRC (AOC 1001)

참고 문헌

데이터시트

Anti-Human Transferrin R/TfR Reference Antibody (AOC 1001, RUO).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human Transferrin R/TfR Reference Antibody (AOC 1001, RUO) (HY036046)

개요

이미지

참고 문헌

데이터시트

SDS