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| 카탈로그 번호 | HB145016 |
|---|---|
| 설명 |
Anti-Human CD75/ST6GAL1 (EBU-141 Tetra) (HB145016) is a research-grade recombinant antibody targeting CD75. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | EBU-141 Tetra |
| 발현 시스템 | Mammalian cells |
| 타겟 | Alpha 2, 6-ST 1, B-cell antigen CD75, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 6-sialyltransferase 1, SIAT1, Sialyltransferase 1, ST6GAL1, ST6Gal I, Beta-galactoside alpha-2, 6-sialyltransferase 1, ST6GalI |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P15907 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | EBU-141Tetra, EBU141Tetra, EBU141Tetra |
| 배경 | Beta-galactoside alpha-2,6-sialyltransferase 1 (CD75/ST6GAL1) is a ~46 kDa protein. Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates. In B lymphocytes, generates neuraminidase-sensitive lymphocyte cell-surface differentiation antigens, such as CDw75, HB-6 and CD76. Sialylates complex-type N-glycans attached on the fragment crystallizable (Fc) of IgGs confering anti-inflammatory effector functions. Preferentially monosialylates the alpha(1->3) mannose antenna of Fc glycoforms with subsequent disialylation occurring at a much slower rate. 1. Bast, BJ. et al. (1992) The Journal of cell biology 116, 423-35. PMID: 1730763 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human CD75/ST6GAL1 (EBU-141 Tetra)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
