Anti-Human Complement C2 Reference Antibody (ARGX-117, RUO) (HY106026)

Name: Anti-Human Complement C2 Reference Antibody (ARGX-117, RUO)
Brand: abinScience
SKU: HY106026
Price: 370 USD
Availability: InStock

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개요

카탈로그 번호	HY106026
설명	Anti-Human Complement C2 Antibody (ARGX-117) (HY106026) is a research-grade recombinant antibody targeting Complement C2. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG
클론 ID	ARGX-117
발현 시스템	Mammalian cells
성질	Recombinant
타겟	Complement C2, C2, C3/C5 convertase
내독소 수준	< 10 EU/mg as determined by LAL method.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P06681
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	ARGX-117, ARGX117, ARGX117
배경	Complement C2 is a ~83 kDa protein. Precursor of the catalytic component of the C3 and C5 convertase complexes, which are part of the complement pathway, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Component C2 is part of the classical, lectin and GZMK complement systems. 1. Rawal, N. et al. (2003) The Journal of biological chemistry 278, 38476-83. PMID: 12878586 2. Milder, FJ. et al. (2006) Structure (London, England : 1993) 14, 1587-97. PMID: 17027507 3. Rawal, N. et al. (2008) The Journal of biological chemistry 283, 7853-63. PMID: 18204047 4. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456 5. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882 6. Héja, D. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 10498-503. PMID: 22691502
참고사항	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Anti-Human Complement C2 Antibody (ARGX-117)

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Anti-Human Complement C2 Reference Antibody (ARGX-117, RUO).pdf

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Anti-Human Complement C2 Reference Antibody (ARGX-117, RUO) (HY106026)

개요

이미지

참고 문헌

데이터시트

SDS