Anti-Human DLL3 Reference Antibody (AMG 119, RUO) (HP628036)

Name: Anti-Human DLL3 Reference Antibody (AMG 119, RUO)
Brand: abinScience
SKU: HP628036
Price: 370 USD
Availability: InStock

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개요

카탈로그 번호	HP628036
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG
클론 ID	AMG 119
발현 시스템	Mammalian cells
타겟	Drosophila Delta homolog 3, Delta3, Delta-like protein 3, DLL3
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q9NYJ7
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	AMG-119, AMG119, AMG119
배경	Delta-like protein 3 (DLL3) is a ~64 kDa protein. Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
참고 문헌	1. Zhou D, et al. Clinical Pharmacology Profile of AMG 119, the First Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting Delta-Like Ligand 3 (DLL3), in Patients with Relapsed/Refractory Small Cell Lung Cancer (SCLC). J Clin Pharmacol. 2024 Mar;64(3):362-370. [HP628036]
참고사항	For research use only. Not suitable for clinical or therapeutic use.