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| 카탈로그 번호 | HB745016 |
|---|---|
| 설명 |
Anti-Human OSM/Oncostatin-M Reference Antibody (GSK 2330811, RUO) (HB745016) is a human monoclonal antibody detecting OSM/Oncostatin-M. Expressed in Mammalian cells.
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | GSK 2330811 |
| 발현 시스템 | Mammalian cells |
| 타겟 | Oncostatin-M, OSM |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P13725 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | GSK-2330811, GSK2330811, GSK2330811 |
| 배경 | Oncostatin-M (OSM) is a ~28 kDa protein. Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). |
| 참고 문헌 | 1. Denton CP, et al. Biological and clinical insights from a randomized phase 2 study of an anti-oncostatin M monoclonal antibody in systemic sclerosis. Rheumatology (Oxford). 2022 Dec 23;62(1):234-242. [HB745016] |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human OSM/Oncostatin-M (GSK 2330811)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
