Anti-Human Prolactin R Reference Antibody (REGN2878-DM1, RUO) (HB801046)

Name: Anti-Human Prolactin R Reference Antibody (REGN2878-DM1, RUO)
Brand: abinScience
SKU: HB801046
Price: 370 USD
Availability: InStock

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개요

카탈로그 번호	HB801046
설명	Anti-Human PRLR (REGN2878-DM1) (HB801046) is a research-grade recombinant antibody targeting PRLR. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG
클론 ID	REGN2878-DM1
발현 시스템	Mammalian cells
타겟	PRLR, PRL-R, Prolactin receptor
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P16471
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	REGN2878-DM1, REGN2878DM1, REGN2878DM1
배경	Prolactin receptor (PRLR) is a ~69 kDa protein. This is a receptor for the anterior pituitary hormone prolactin (PRL). Acts as a prosurvival factor for spermatozoa by inhibiting sperm capacitation through suppression of SRC kinase activation and stimulation of AKT. Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling.
참고사항	For research use only. Not suitable for clinical or therapeutic use.