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| 카탈로그 번호 | HP075016 |
|---|---|
| 설명 |
Anti-Human SLC2A8/GLUT8 (VB1-050) (HP075016) is a research-grade recombinant antibody targeting Glucose transporter type X1. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | VB1-050 |
| 발현 시스템 | Mammalian cells |
| 성질 | Recombinant |
| 타겟 | Glucose transporter type X1, GLUT-8, Glucose transporter type 8, GLUTX1, SLC2A8, Solute carrier family 2, facilitated glucose transporter member 8, GLUT8 |
| 내독소 수준 | < 10 EU/mg as determined by LAL method. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | Q9NY64 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | VB1-050, VB1050, VB1050 |
| 배경 | Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8GLUT8) is a ~50 kDa protein. Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Facilitates hepatic influx of dietary trehalose, which in turn inhibits glucose and fructose influx triggering a starvation signal and hepatic autophagy through activation of AMPK and ULK1. Also able to mediate the transport of dehydroascorbate. 1. Mayer, AL. et al. (2016) Scientific reports 6, 38586. PMID: 27922102 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human SLC2A8GLUT8 (VB1-050)
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