中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HY096016 |
|---|---|
| 설명 |
Anti-Human TDGF1/CRIPTO (BIIB015) (HY096016) is a research-grade recombinant antibody targeting Cripto-1 growth factor. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG |
| 클론 ID | BIIB015 |
| 발현 시스템 | Mammalian cells |
| 타겟 | Cripto-1 growth factor, Teratocarcinoma-derived growth factor 1, TDGF1, CRIPTO, Epidermal growth factor-like cripto protein CR1, CRGF |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P13385 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | BIIB015 |
| 배경 | Protein Cripto (TDGF1) is a ~21 kDa protein. GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. 1. Lee, GH. et al. (2016) The Journal of cell biology 215, 705-718. PMID: 27881714 2. Bianco, C. et al. (2002) Molecular and cellular biology 22, 2586-97. PMID: 11909953 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Anti-Human TDGF1/CRIPTO (BIIB015)
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
