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| 카탈로그 번호 | YP862016 |
|---|---|
| 설명 |
Bavituximab (YP862016) is a research-grade recombinant antibody targeting Phosphatidylserine. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | General |
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 숙주 종 | Chimeric |
| 클론성 | Monoclonal |
| 이소타입 | IgG1-kappa |
| 발현 시스템 | Mammalian cells |
| 타겟 | Phosphatidylserine |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | 1446756-47-3 |
| RRID | Anti-Phosphatidylserine Reference Antibody (Bavituximab, RUO) (abinScience Cat# YP862016, RRID:AB_3751823) |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C. |
| 대체 이름 | Tarvacinch3 G4, CAS: 648904-28-3 |
| 배경 | Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity. Bavituximab plus Paclitaxel and Carboplatin, have enhanced inhibition on non-small-cell lung cancer. • Phosphatidylserine and the human brain., PMID:25933483 • The distribution and function of phosphatidylserine in cellular membranes., PMID:20192774 • Phosphatidylserine transport in cell life and death., PMID:37413778 • Phosphatidylserine., PMID:10541030 • Phosphatidylserine: A Novel Target for Ischemic Stroke Treatment., PMID:39456225 • Phosphatidylserine for the Treatment of Pediatric Attention-Deficit/Hyperactivity Disorder: A Systematic Review and Meta-Analysis., PMID:33539192 • Phosphatidylserine externalization as immune checkpoint in cancer., PMID:38573347 • Phosphatidylserine: A comprehensive overview of synthesis, metabolism, and nutrition., PMID:39097133 • Dynamics of phagocytosis mediated by phosphatidylserine., PMID:36281986 • Flagging fusion: Phosphatidylserine signaling in cell-cell fusion., PMID:33581114 |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Bavituximab.
SDS-PAGE for Research Grade Bavituximab
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