Anti-Human BCMA/TNFRSF17 Reference Antibody (Belantamab, RUO) (HX959016)

Name: Anti-Human BCMA/TNFRSF17 Reference Antibody (Belantamab, RUO)
Brand: abinScience
SKU: HX959016
Price: 176 USD
Availability: InStock

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100ug
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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HX959016
설명	Belantamab (HX959016) is a research-grade recombinant antibody targeting CD269. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1-kappa
테스트된 응용 분야	WB, FCM
타겟	B-cell maturation protein, BCM, BCMA, CD269, TNFRSF17, Tumor necrosis factor receptor superfamily member 17
내독소 수준	< 10 EU/mg
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q02223
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	BCMA, 2857916, GSK2857916, J6M0, J6M0-mcMMAF, 2061894-48-0
배경	Tumor necrosis factor receptor superfamily member 17 (CD269/BCMA) is a ~20 kDa protein. Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. CD269 is the therapeutic target of teclistamab (Tecvayli).
참고사항	For research use only. Not suitable for clinical or therapeutic use.

이미지

SEC-HPLC

SEC-HPLC detection for Research Grade Belantamab.
Bioactivity

Detects CD269/TNFRSF17/BCMA in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Anti-Human BCMA/TNFRSF17 Reference Antibody (Belantamab, RUO)
Flow CytoMetry

Flow-cytometry using anti-human CD269 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human CD269 monoclonal antibody (Catalog: HX959016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-CD269 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD269 (Catalog No: HX959011)
Lane 2: negative control