Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO) (HV212016)

Name: Anti-Human BAFF/BLyS/TNFSF13B Reference Antibody (Belimumab, RUO)
Brand: abinScience
SKU: HV212016
Price: 176 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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100ug
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25mg
50mg
100mg

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HV212016
설명	Belimumab (HV212016) is a research-grade recombinant antibody targeting CD257. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1-lambda
발현 시스템	Mammalian cells
테스트된 응용 분야	WB
타겟	BAFF, ZTNF4, BLYS, Tumor necrosis factor ligand superfamily member 13B, Dendritic cell-derived TNF-like molecule, TALL-1, TNF- and APOL-related leukocyte expressed ligand 1, BLyS, B lymphocyte stimulator, TNFSF13B, CD257, TNFSF20, TALL1, B-cell-activating factor
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q9Y275
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	LymphoStat-B, hBlySmAb-1.1, 356547-88-1
배경	Tumor necrosis factor ligand superfamily member 13B (CD257/BAFF) is a ~31 kDa protein. Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.
참고사항	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

이미지

Bioactivity

SEC-HPLC detection for Research Grade Belimumab.
SDS-PAGE

SDS-PAGE for Research Grade Belimumab
Western blot

Western blot analysis was performed using anti-CD257/BAFF/TNFSF13B monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD257/BAFF/TNFSF13B (Catalog No: HV212011)
Lane 2: negative control