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| 카탈로그 번호 | HF822016 | ||||||
|---|---|---|---|---|---|---|---|
| 설명 |
Biciromab (HF822016) is a research-grade recombinant antibody targeting FGB. Produced in mammalian cells with native-like glycosylation.
Highlights
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| 종 반응성 | Human | ||||||
| 응용 분야 | ELISA, WB, Bioactivity: FACS, Functional assay, Research in vivo | ||||||
| 숙주 종 | Mouse | ||||||
| 클론성 | Monoclonal | ||||||
| 이소타입 | IgG1-kappa | ||||||
| 발현 시스템 | Mammalian cells | ||||||
| 타겟 | FGB, Fibrinogen beta chain | ||||||
| 내독소 수준 | < 10 EU/mg | ||||||
| 순도 | >95% purity as determined by SDS-PAGE. | ||||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||||
| 등록번호 | P02675 | ||||||
| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 대체 이름 | Indium(111In)biciromab, T2G1, 138783-13-8 | ||||||
| 배경 | Fibrinogen beta chain (FGB) is a ~55 kDa protein. Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. | ||||||
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Biciromab.
SDS-PAGE for Research Grade Biciromab
Western blot analysis was performed using anti-FGB monoclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
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