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Anti-Human PD-L1 & TGF-beta RII Reference Antibody (Bintrafusp Alfa, RUO) (HV974116)

Anti-Human PD-L1 & TGF-beta RII Reference Antibody (Bintrafusp Alfa, RUO)
Anti-Human PD-L1 & TGF-beta RII Reference Antibody (Bintrafusp Alfa, RUO)
가격(USD):
사양:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
수량:
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  • 개요

  • 이미지

  • 참고 문헌

  • 데이터시트

  • SDS

개요
카탈로그 번호HV974116
설명
Bintrafusp Alfa (HV974116) is a research-grade recombinant antibody targeting CD1. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성Human
응용 분야ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종Human
클론성Monoclonal
이소타입IgG1-lambda
타겟 B7 homolog 1, B7-H1, B7H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, EC:2.7.11.30, TGF-beta receptor type II, TGF-beta receptor type-2, TGF-beta type II receptor, TGFBR2, TGFR-2, TbetaR-II, Transforming growth factor-beta receptor type II
내독소 수준 < 10 EU/mg
순도 >95% as determined by SDS-PAGE.
정제 Protein A/G purified from cell culture supernatant.
등록번호 Q9NZQ7 & P37173
형태 Liquid
저장 완충액 0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer.
참고사항 For research use only. Not suitable for clinical or therapeutic use.
이미지
  • Anti-Human PD-L1 & TGF-beta RII Reference Antibody (Bintrafusp Alfa, RUO)

    Bioactivity

    SEC-HPLC detection for Research Grade Bintrafusp Alfa.

참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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