

| 카탈로그 번호 | CY257016 | ||||
|---|---|---|---|---|---|
| 설명 |
Blontuvetmab (CY257016) is a research-grade recombinant antibody targeting CD20. Produced in mammalian cells with native-like glycosylation.
Highlights
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| 종 반응성 | Canine | ||||
| 응용 분야 | ELISA, Bioactivity: FCM, Functional assay, Research in vivo | ||||
| 숙주 종 | Canine | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2-kappa-lambda | ||||
| 타겟 | B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, CD20, Leukocyte surface antigen Leu-16, MS4A1, Membrane-spanning 4-domains subfamily A member 1 | ||||
| 내독소 수준 | < 10 EU/mg | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q3C2E2 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 대체 이름 | AT-004, VT-007, 1608112-78-2 | ||||
| 배경 | B-lymphocyte antigen CD20 (MS4A1) is a ~33 kDa protein. B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR. CD20 is the therapeutic target of rituximab (MabThera) and obinutuzumab (Gazyva). | ||||
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Blontuvetmab.


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