Anti-Human Von Willebrand Factor Reference Antibody (Caplacizumab, RUO) (HY255016)

Name: Anti-Human Von Willebrand Factor Reference Antibody (Caplacizumab, RUO)
Brand: abinScience
SKU: HY255016
Price: 176 USD
Availability: InStock

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개요

카탈로그 번호	HY255016
설명	Caplacizumab (HY255016) is a research-grade recombinant antibody targeting von Willebrand antigen II. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	VH-VH
발현 시스템	Mammalian cells
타겟	von Willebrand antigen II, von Willebrand factor, F8VWF, vWF, VWF
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P04275
형태	Liquid
저장 완충액	20 mM citric acid, 6.2% sucrose, 0.01% Tween80 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	ALX-0081, PMP12A2h1-linkerAAA-PMP12A2h1, caplacizumab-yhdp, 915810-67-2
배경	von Willebrand factor (VWF) is a ~309 kDa protein. Important in the maintenance of hemostasis, it promotes adhesion of platelets to the sites of vascular injury by forming a molecular bridge between sub-endothelial collagen matrix and platelet-surface receptor complex GPIb-IX-V. Also acts as a chaperone for coagulation factor VIII, delivering it to the site of injury, stabilizing its heterodimeric structure and protecting it from premature clearance from plasma.
참고사항	For research use only. Not suitable for clinical or therapeutic use.