Anti-Human TROP-2 Reference Antibody (Datopotamab, RUO) (HY373026)

Name: Anti-Human TROP-2 Reference Antibody (Datopotamab, RUO)
Brand: abinScience
SKU: HY373026
Price: 176 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HY373026
설명	Datopotamab (HY373026) is a research-grade recombinant antibody targeting Pancreatic carcinoma marker protein GA733-1. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1-kappa
발현 시스템	Mammalian cells
테스트된 응용 분야	WB, FCM
타겟	Pancreatic carcinoma marker protein GA733-1, Tumor-associated calcium signal transducer 2, M1S1, TROP2, TACSTD2, Cell surface glycoprotein Trop-2, GA733-1, Membrane component chromosome 1 surface marker 1
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P09758
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	DS-1062, DS-1062a, Datopotamabderuxtecan, 2267989-53-5
배경	Tumor-associated calcium signal transducer 2 (TACSTD2/TROP2) is a ~35 kDa protein. May function as a growth factor receptor. TACSTD2 is the therapeutic target of sacituzumab govitecan (Trodelvy).
참고사항	For research use only. Not suitable for clinical or therapeutic use.

이미지

Bioactivity

Detects Human TROP2 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Datopotamab.
Flow CytoMetry

Flow-cytometry using anti-human TACSTD2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human TACSTD2 monoclonal antibody (Catalog: HY373026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Western blot

Western blot analysis was performed using anti-TACSTD2/TROP2 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human TACSTD2/TROP2 (Catalog No: HY373011)
Flow cytometry

Flow-cytometry using FITC anti-human TACSTD2 antibody. Hela cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human TACSTD2 monoclonal antibody (Catalog HY373026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.
Flow cytometry

Flow-cytometry using FITC anti-human TACSTD2 antibody. MCF7 cells were stained with an irrelevant antibody (Blue Histogram) or an FITC anti-human TACSTD2 monoclonal antibody (Catalog HY373026, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.