Anti-Human Osteoactivin/GPNMB Reference Antibody (Glembatumumab, RUO) (HC358016)

Name: Anti-Human Osteoactivin/GPNMB Reference Antibody (Glembatumumab, RUO)
Brand: abinScience
SKU: HC358016
Price: 176 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HC358016
설명	Glembatumumab (HC358016) is a research-grade recombinant antibody targeting NMB. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG2-kappa
발현 시스템	Mammalian cells
타겟	NMB, Hematopoietic growth factor inducible neurokinin-1 type, HGFIN, GPNMB, Transmembrane glycoprotein NMB
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q14956
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	CDX-011(DOX), CR011, glembatumumabvedotin(ADC), 1020264-78-1
배경	Transmembrane glycoprotein NMB (GPNMB) is a ~63 kDa protein. Could be a melanogenic enzyme.
참고사항	For research use only. Not suitable for clinical or therapeutic use.

이미지

SEC-HPLC

SEC-HPLC detection for Research Grade Glembatumumab.
Bioactivity

Detects GPNMB in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Glembatumumab.
Flow CytoMetry

Flow-cytometry using anti-human GPNMB antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human GPNMB monoclonal antibody (Catalog: HC358016) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.