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Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO) (HX126026)

Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)
가격(USD):
사양:
  • 100ug
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
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  • 개요

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개요
카탈로그 번호HX126026
설명
Gresonitamab (HX126026) is a research-grade recombinant antibody targeting CD3. Produced in mammalian cells with native-like glycosylation.
Highlights
  • ●Research Grade — For PK/PD studies, assay development, and ADA research.
  • ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성Human
응용 분야ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종Human
클론성Monoclonal
이소타입(scFv-heavy-kappa)-(scFv-heavy-lambda)-scFc
테스트된 응용 분야 FCM
타겟 CLDN18.2, Claudin-18.2, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E
내독소 수준 < 10 EU/mg
순도 >95% as determined by SDS-PAGE.
정제 Protein A/G purified from cell culture supernatant.
등록번호 P56856-2 & P07766
형태 Liquid
저장 완충액 0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름Bispecific, AMG910, AMG-910, AMG9102413817-97-5
배경Gresonitamab (AMG 910) is a half-life extended (HLE) bispecific T-cell engager (BiTE) antibody targets CD3-positive T cells and CLDN18.2-expressing tumor cells. Gresonitamab can be used for the research of adenocarcinoma.
참고사항 For research use only. Not suitable for clinical or therapeutic use.
Isotype Control Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
이미지
  • Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)

    SDS-PAGE

    SDS-PAGE for Research Grade Gresonitamab

  • Anti-Human Claudin-18.2 & CD3 epsilon Bispecific Reference Antibody (Gresonitamab, RUO)

    Flow cytometry

    Flow-cytometry APC using anti-human CLDN18.2 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an APC anti-human CLDN18.2 monoclonal antibody (Catalog HX126026) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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