Anti-Human BCMA/TNFRSF17 Reference Antibody (Ispectamab, RUO) (HX959076)

Name: Anti-Human BCMA/TNFRSF17 Reference Antibody (Ispectamab, RUO)
Brand: abinScience
SKU: HX959076
Price: 176 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HX959076
설명	Ispectamab (HX959076) is a research-grade recombinant antibody targeting CD269. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG1-kappa
테스트된 응용 분야	WB
타겟	B-cell maturation protein, BCM, BCMA, CD269, TNFRSF17, Tumor necrosis factor receptor superfamily member 17
내독소 수준	< 10 EU/mg
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q02223
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	BMS-986352, CC-99712, CC99712, CC99712, SP8919, 2413386-21-5
배경	Tumor necrosis factor receptor superfamily member 17 (CD269/BCMA) is a ~20 kDa protein. Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. CD269 is the therapeutic target of teclistamab (Tecvayli).
참고사항	For research use only. Not suitable for clinical or therapeutic use.

이미지

Western blot

Western blot analysis was performed using anti-CD269 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD269 (Catalog No: HX959012)
Lane 2: negative control
SDS-PAGE

SDS-PAGE for Research Grade Ispectamab.
Bioactivity

Detects recombinant human CD269/TNFRSF17/BCMA (Catalog No: HX959012) in indirect ELISA