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| 카탈로그 번호 | HF977036 |
|---|---|
| 설명 |
Livmoniplimab (HF977036) is a research-grade recombinant antibody targeting Transforming growth factor beta-1 proprotein. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Bioactivity: FCM, Functional assay, Research in vivo |
| 숙주 종 | Human |
| 클론성 | Monoclonal |
| 이소타입 | IgG4-kappa |
| 타겟 | LAP, Latency-associated peptide, TGF-beta-1, TGFB, TGFB1, Transforming growth factor beta-1, Transforming growth factor beta-1 proprotein, D11S833E, GARP, Garpin, Glycoprotein A repetitions predominant, LRRC32, Leucine-rich repeat-containing protein 32, Transforming growth factor beta activator LRRC32 |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P01137 & Q14392 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Bispecific, ABBV-151, ARGX-115, MHG-8, MHGARP-8, PR-17628442412004-88-5 |
| 배경 | Livmoniplimab (ABBV-151) is a monoclonal antibody against GARP/TGF-β1 that can inhibit the release of active TGF-β1. Livmoniplimab has anti-tumor activity in colon cancer mice. Livmoniplimab can be used for the study of locally advanced or metastatic solid tumors. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207) |
SEC-HPLC detection for Research Grade Livmoniplimab.
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