Anti-Human IL-17C Reference Antibody (Mor106, RUO) (HV335026)

Name: Anti-Human IL-17C Reference Antibody (Mor106, RUO)
Brand: abinScience
SKU: HV335026
Price: 370 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

수량:

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HV335026

설명

MOR106 (HV335026) is a research-grade recombinant antibody targeting Cytokine CX2.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.

종 반응성

Human

응용 분야

ELISA, FACS, Functional assay

숙주 종

Human

클론성

Monoclonal

이소타입

IgG1, kappa

타겟

Cytokine CX2, IL-17C, IL17C, Interleukin-17C

내독소 수준

< 10 EU/mg

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

Q9P0M4

형태

Liquid

저장 완충액

0.01M PBS pH 7.4

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:2000-1:20000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Interleukin-17C (IL17C) is a ~21 kDa protein. Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and pro-inflammatory molecules for host defense by signaling through the NF-kappa-B and MAPK pathways. Acts synergically with IL22 in inducing the expression of antibacterial peptides, including S100A8, S100A9, REG3A and REG3G. Synergy is also observed with TNF and IL1B in inducing DEFB2 from keratinocytes. Depending on the type of insult, may have both protective and pathogenic properties, either by maintaining epithelial homeostasis after an inflammatory challenge or by promoting inflammatory phenotype.

참고사항

For research use only.

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