Anti-Human GDNF Reference Antibody (Nadecnemab, RUO) (HT009016)

Name: Anti-Human GDNF Reference Antibody (Nadecnemab, RUO)
Brand: abinScience
SKU: HT009016
Price: 176 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HT009016
설명	Nadecnemab (HT009016) is a research-grade recombinant antibody targeting GFR-alpha-3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG4-Kappa
발현 시스템	Mammalian cells
타겟	GFR-alpha-3, GDNF receptor alpha-3, GDNF family receptor alpha-3, GDNFR-alpha-3, GFRA3
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	O60609
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	REGN5069, 2377679-19-9
배경	GDNF family receptor alpha-3 (GFRA3) is a ~44 kDa protein. Receptor for artemin (ARTN), a growth factor that supports the survival of sensory and sympathetic peripheral neurons. ARTN-binding leads to autophosphorylation and activation of the RET receptor. 1. Li, J. et al. (2019) eLife 8. PMID: 31535977 2. Baloh, RH. et al. (1998) Neuron 21, 1291-302. PMID: 9883723
참고사항	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107)

이미지

SEC-HPLC

SEC-HPLC detection for Research Grade Nadecnemab.
Bioactivity

Detects GFRA3 in indirect ELISAs.

참고 문헌

데이터시트

Anti-Human GDNF Reference Antibody (Nadecnemab, RUO).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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어세이 키트

Anti-Human GDNF Reference Antibody (Nadecnemab, RUO) (HT009016)

개요

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참고 문헌

데이터시트

SDS

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