Anti-Human IL-31RA Reference Antibody (Nolavetbart, RUO) (CV121016)

Name: Anti-Human IL-31RA Reference Antibody (Nolavetbart, RUO)
Brand: abinScience
SKU: CV121016
Price: 176 USD
Availability: InStock

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개요
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개요

카탈로그 번호	CV121016
설명	Nolavetbart (CV121016) is a research-grade recombinant antibody targeting IL31RA. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Canine
응용 분야	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종	Canine
클론성	Monoclonal
이소타입	IgG2-kappa
발현 시스템	Mammalian cells
성질	Recombinant
타겟	IL31RA
내독소 수준	< 10 EU/mg as determined by LAL method.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	A0A8I3Q391
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	2750248-93-0
배경	Interleukin-31 receptor subunit alpha (IL31RA) is a ~82 kDa protein. Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. 1. Ghilardi, N. et al. (2002) The Journal of biological chemistry 277, 16831-6. PMID: 11877449 2. Diveu, C. et al. (2003) The Journal of biological chemistry 278, 49850-9. PMID: 14504285 3. Dreuw, A. et al. (2004) The Journal of biological chemistry 279, 36112-20. PMID: 15194700 4. Diveu, C. et al. (2004) European cytokine network 15, 291-302. PMID: 15627637 5. Dillon, SR. et al. (2004) Nature immunology 5, 752-60. PMID: 15184896
참고사항	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for Research Grade Nolavetbart

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Anti-Human IL-31RA Reference Antibody (Nolavetbart, RUO).pdf

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Anti-Human IL-31RA Reference Antibody (Nolavetbart, RUO) (CV121016)

개요

이미지

참고 문헌

데이터시트

SDS