Anti-Human CD39/ENTPD1 Reference Antibody (Perenostobart, RUO) (HW564056)

Name: Anti-Human CD39/ENTPD1 Reference Antibody (Perenostobart, RUO)
Brand: abinScience
SKU: HW564056
Price: 176 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
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개요

카탈로그 번호	HW564056
설명	Perenostobart (HW564056) is a research-grade recombinant antibody targeting CD39. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
클론성	Monoclonal
이소타입	IgG4-kappa
발현 시스템	Mammalian cells
타겟	Ecto-ATP diphosphohydrolase 1, NTPDase 1, ENTPD1, Ecto-ATPase 1, Ecto-apyrase, Ecto-ATPDase 1, Ectonucleoside triphosphate diphosphohydrolase 1, CD39, Lymphoid cell activation antigen
내독소 수준	< 10 EU/mg
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P49961
형태	Liquid
저장 완충액	0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	2643331-31-9
배경	Ectonucleoside triphosphate diphosphohydrolase 1 (CD39/ENTPD1) is a ~57 kDa protein. Catalyzes the hydrolysis of nucleoside triphosphates (NTPs) and diphosphates (NDPs) (Probable). The enzyme sequentially removes phosphate groups in two successive steps, converting NTPs to nucleoside monophosphates (NMPs) via NDP intermediates (Probable). This activity contributes to the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow. 1. Christoforidis, S. et al. (1995) European journal of biochemistry 234, 66-74. PMID: 8529670 2. Wang, TF. et al. (1996) The Journal of biological chemistry 271, 9898-901. PMID: 8626624 3. Kaczmarek, E. et al. (1996) The Journal of biological chemistry 271, 33116-22. PMID: 8955160 4. Robson, SC. et al. (1997) The Journal of experimental medicine 185, 153-63. PMID: 8996251
참고사항	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Human IgG4 (S228P) Recombinant Isotype Control Antibody (13R4) (HP298207)