Anti-Human DPEP3 Reference Antibody (Pintumomab, RUO) (HV426016)

Name: Anti-Human DPEP3 Reference Antibody (Pintumomab, RUO)
Brand: abinScience
SKU: HV426016
Price: 326 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호	HV426016
설명	Pintumomab (HV426016) is a research-grade recombinant antibody targeting DPEP3. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FCM, Functional assay, Research in vivo
숙주 종	Mouse
클론성	Monoclonal
이소타입	IgG1-kappa
발현 시스템	Mammalian cells
성질	Recombinant
타겟	DPEP3, Dipeptidase 3
내독소 수준	< 10 EU/mg as determined by LAL method.
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q9H4B8
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
대체 이름	170, 339177-26-3
배경	Dipeptidase 3 (DPEP3) is a ~53 kDa protein. Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem. The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide. A tyrosine (instead of histidine) at position 269 reduces affinity for the beta zinc and may cause substrate steric hindrance. 1. Hayashi, K. et al. (2020) Journal of structural biology 211, 107512. PMID: 32325220
참고사항	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21) (MV080207)

이미지

SDS-PAGE

SDS-PAGE for Research Grade Pintumomab

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데이터시트

Anti-Human DPEP3 Reference Antibody (Pintumomab, RUO).pdf

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Formula

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Anti-Human DPEP3 Reference Antibody (Pintumomab, RUO) (HV426016)

개요

이미지

참고 문헌

데이터시트

SDS