Anti-Human CD4 Reference Antibody (Semzuvolimab, RUO) (HF998086)

Name: Anti-Human CD4 Reference Antibody (Semzuvolimab, RUO)
Brand: abinScience
SKU: HF998086
Price: 176 USD
Availability: InStock

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가격(USD):

사양:

100ug
1mg
5mg
10mg
25mg
50mg
100mg

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HF998086

설명

Semzuvolimab (HF998086) is a research-grade recombinant antibody targeting CD4. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

종 반응성

Human

응용 분야

ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB

숙주 종

Chimeric

클론성

Monoclonal

이소타입

IgG1-kappa

테스트된 응용 분야

타겟

CD4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

내독소 수준

< 10 EU/mg

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P01730

형태

Liquid

저장 완충액

0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

대체 이름

UB421, UB-421, UB421, 2409099-32-5

배경

T-cell surface glycoprotein CD4 is a ~51 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.

참고사항

For research use only. Not suitable for clinical or therapeutic use.

Isotype Control

Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)

이미지

SDS-PAGE

SDS-PAGE for Research Grade Semzuvolimab.
Bioactivity

Detects recombinant CD4 (Catalog No: HF998011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-CD4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD4 (Catalog No: HF998011)
Lane 2: Negative control
Western blot

Western blot analysis was performed using anti-CD4 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD4 (Catalog No: HF998012)
Lane 2: Negative control