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| 카탈로그 번호 | JN822016 |
|---|---|
| 설명 |
Setoxaximab (JN822016) is a research-grade recombinant antibody targeting shiga toxin type 2stx2A. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Escherichia coli |
| 응용 분야 | ELISA, Bioactivity: FACS, Functional assay, Research in vivo |
| 숙주 종 | Chimeric |
| 클론성 | Monoclonal |
| 이소타입 | IgG1-kappa |
| 발현 시스템 | Mammalian cells |
| 타겟 | shiga toxin type 2stx2A |
| 내독소 수준 | < 10 EU/mg |
| 순도 | >95% purity as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P09385 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | Shigamabs(drugnameforthecombinationofpritoxaximabandsetoxaximab), caStx2, 1351470-17-1 |
| 배경 | Shiga-like toxin 2 subunit A (shiga toxin type 2Astx2A) is a ~35 kDa protein. The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SEC-HPLC detection for Research Grade Setoxaximab.
SDS-PAGE for Research Grade Setoxaximab
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