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| 카탈로그 번호 | HY428026 |
|---|---|
| 설명 |
Sotatercept (HY428026) is a research-grade recombinant antibody targeting EDF. Produced in mammalian cells with native-like glycosylation.
Highlights
|
| 종 반응성 | Human |
| 응용 분야 | ELISA, Functional assay, Research in vivo |
| 클론성 | Monoclonal |
| 이소타입 | Fusion - [ACVR2A (activin A receptor type 2A, ActR-II, ActRIIA)]2 - IGHG1 Fc (Fragment constant) |
| 발현 시스템 | Mammalian cells |
| 성질 | Recombinant |
| 타겟 | EDF, Erythroid differentiation protein, Activin beta-A chain, INHBA, Inhibin beta A chain |
| 내독소 수준 | < 10 EU/mg as determined by LAL method. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P08476 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 대체 이름 | ACE-011, ACTRIIA-Fc, MK7962, MK-7962, MK7962, Sotatercept(USAN/INN), SOTATERCEPT-CSRK, WINREVAIR, 1001080-50-7 |
| 배경 | Inhibin beta A chain (INHBA) is a ~47 kDa protein. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. |
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for Research Grade Sotatercept
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