中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HX959196 | ||||
|---|---|---|---|---|---|
| 설명 |
Vonsetamig (HX959196) is a research-grade recombinant antibody targeting CD269. Produced in mammalian cells with native-like glycosylation.
Highlights
|
||||
| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, Bioactivity: FCM, Functional assay, Research in vivo, WB | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG4-kappa | ||||
| 테스트된 응용 분야 | WB, FCM | ||||
| 타겟 | B-cell maturation protein, BCM, BCMA, CD269, TNFRSF17, Tumor necrosis factor receptor superfamily member 17, CD3E, CD3e, T-cell surface antigen T3/Leu-4 epsilon chain, T-cell surface glycoprotein CD3 epsilon chain, T3E | ||||
| 내독소 수준 | < 10 EU/mg | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | Q02223 & P07766 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||
| 제품 사용 정보 |
| ||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 대체 이름 | 2408319-33-3 | ||||
| 배경 | Teclistamab is an active T cell–redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma | ||||
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. | ||||
| Isotype Control | Human IgG4 (S228P) Recombinant Isotype Control Antibody (SAA0184) (HP298107) |
SDS-PAGE for Research Grade Vonsetamig.
Flow-cytometry using anti-human CD3E antibody. Jurkat cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD3E monoclonal antibody (Catalog HX959196, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Flow-cytometry using anti-human CD269 antibody. Transfected cells were stained with an irrelevant antibody (Blue Histogram) or an anti-human CD269 monoclonal antibody (Catalog HX959196, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Human IgG H&L Polyclonal Antibody, FITC (abinScience: HF690414) and cells analysed on a NovoCyte Flow Cytometer.
Detects recombinant CD269 (Catalog No: HX959012) in indirect ELISA.
Western blot analysis was performed using anti-CD3E monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD3E (Catalog No: HY057021)
Lane 2: Negative control
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
