Pollen Allergen Research Reagents

Bet v 1 (Birch) — The major birch pollen allergen and prototype of the PR-10 protein family. Bet v 1 sensitization affects over 100 million people in Northern Europe and is the primary driver of birch-apple oral allergy syndrome (OAS) through cross-reactivity with Mal d 1, Pru p 1, and other PR-10 homologs in fruits and vegetables.
→ Browse Bet v allergen proteins

Phl p 1 / Phl p 5 (Timothy Grass) — Major allergens of timothy grass (Phleum pratense), the most important grass pollen source. Phl p 1 is a β-expansin with broad cross-reactivity across grass species; Phl p 5 is a ribonuclease with high IgE prevalence in grass-allergic patients. Both are key components in grass pollen sublingual immunotherapy (SLIT) tablet formulations.
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Cry j 1 / Cry j 2 (Japanese Cedar) — Major allergens of Cryptomeria japonica (sugi), causing seasonal allergic rhinitis in over 40% of the Japanese population. Cry j 1 is a pectate lyase; Cry j 2 is a polygalacturonase. Cross-reactive with Cha o 1/2 from Japanese cypress (Chamaecyparis obtusa).
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Amb a 1 (Ragweed) — The dominant allergen of short ragweed (Ambrosia artemisiifolia), the most important weed pollen in North America. Amb a 1 is a pectate lyase that accounts for over 90% of ragweed-specific IgE binding. Ragweed is an invasive species expanding across Europe, making Amb a 1 an increasingly global sensitization marker.
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1. Matricardi PM, et al. EAACI Molecular Allergology User’s Guide. Pediatr Allergy Immunol. 2016;27(Suppl 23):1-250. DOI

2. Breiteneder H, et al. Molecular and biochemical classification of plant-derived food allergens. J Allergy Clin Immunol. 2004;113(5):821-830. DOI