Anti-Mouse MAdCAM-1 Recombinant Antibody (MECA-89) (MC589023)

Name: Anti-Mouse MAdCAM-1 Recombinant Antibody (MECA-89)
Brand: abinScience
SKU: MC589023
Price: 191 USD
Availability: InStock

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개요

카탈로그 번호	MC589023
종 반응성	Mouse
응용 분야	IP, WP, Block, FCM, IHC
숙주 종	Rat
클론성	Monoclonal
이소타입	IgG2a, kappa
클론 ID	MECA-89
타겟	MAdCAM-1, Madcam1, Mucosal addressin cell adhesion molecule 1, mMAdCAM-1
내독소 수준	< 10 EU/mg
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q61826
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경	Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) is a ~43 kDa protein. Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both the integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Both isoform 1 and isoform 2 can adhere to integrin alpha-4/beta-7. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
참고사항	For research use only

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데이터시트

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개요