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| 카탈로그 번호 | VK059023 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-pan-Ebola virus Nucleoprotein Antibody (SAA2995) (VK059023) is a monoclonal antibody detecting Nucleoprotein in ELISA. Suitable for Bundibugyo virus (BDBV), Tai Forest ebolavirus (TAFV) (Cote d'Ivoire Ebola virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus).
Highlights
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| 종 반응성 | Bundibugyo virus (BDBV), Tai Forest ebolavirus (TAFV) (Cote d'Ivoire Ebola virus), Zaire ebolavirus (ZEBOV) (Zaire Ebola virus) | ||||
| 응용 분야 | ELISA | ||||
| 클론성 | Monoclonal | ||||
| 클론 ID | SAA2995 | ||||
| 타겟 | Nucleoprotein | ||||
| 내독소 수준 | < 10 EU/mg as determined by LAL method. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||
| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Nucleoprotein (NP) is a ~56 kDa protein. Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. | ||||
| 참고사항 | For research use only. |
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