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| 카탈로그 번호 | HV580013 |
|---|---|
| 설명 |
Anti-Human CD57/B3GAT1 Recombinant Antibody (HNK-1/Leu-7) (HV580013) is a mouse monoclonal antibody detecting CD57/B3GAT1 in ELISA, FCM, Functional assay. Suitable for General.
Highlights
|
| 종 반응성 | General |
| 응용 분야 | ELISA, FCM, Functional assay |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgM, kappa |
| 내독소 수준 | < 10 EU/mg as determined by LAL method. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 배경 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 (CD57/B3GAT1) is a ~38 kDa protein. Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| 참고사항 | For research use only. |
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