中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HV999014 | ||||||
|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Human IL-22 Polyclonal Antibody (HV999014) is a rabbit polyclonal antibody detecting IL-22 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
||||||
| 종 반응성 | Human | ||||||
| 응용 분야 | ELISA, IHC, WB | ||||||
| 숙주 종 | Rabbit | ||||||
| 클론성 | Polyclonal | ||||||
| 이소타입 | IgG | ||||||
| 면역원 | E. coli - derived recombinant Human IL22 (Ala34-Ile179). | ||||||
| 타겟 | RecName: Full=Interleukin-22; Short=IL-22; AltName: Full=Cytokine Zcyto18; AltName: Full=IL-10-related T-cell-derived-inducible factor; Short=IL-TIF; Flags: Precursor, IL22, IL-22; Cytokine Zcyto18; IL-10-related T-cell-derived-inducible factor; IL-TIF, /evidence=ECO:0000269|PubMed:15340161., Interleukin-22. /id=PRO_0000015383., Interleukin 22 IL-10-related T-cell-derived-inducible factor; pfam14565, /evidence=ECO:0000269|PubMed:18599299., /evidence=ECO:0007829|PDB:3DLQ., /evidence=ECO:0007829|PDB:3DLQ., N-linked (GlcNAc...) asparagine. /evidence=ECO:0000269|PubMed:15983417., N-linked (GlcNAc...) asparagine. /evidence=ECO:0000255., /evidence=ECO:0007829|PDB:1M4R., /evidence=ECO:0007829|PDB:3DLQ., /evidence=ECO:0007829|PDB:3DLQ., /evidence=ECO:0007829|PDB:3DLQ., /evidence=ECO:0000269|PubMed:18599299., N-linked (GlcNAc...) asparagine. /evidence=ECO:0000269|PubMed:15983417., /evidence=ECO:0007829|PDB:3DLQ., /evidence=ECO:0007829|PDB:3DLQ., /evidence=ECO:0007829|PDB:3DLQ., /evidence=ECO:0007829|PDB:3DLQ., /evidence=ECO:0007829|PDB:3DLQ., S -> G (in dbSNP:rs2227507). /evidence=ECO:0000269|Ref.5. /id=VAR_013078., /evidence=ECO:0007829|PDB:3DLQ. | ||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||
| 정제 | Purified by antigen affinity column. | ||||||
| 등록번호 | Q9GZX6 | ||||||
| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||||
| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| 제품 사용 정보 |
| ||||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 배경 | Interleukin-22 (Interleukin-22,Cytokine Zcyto18,IL-22,ZCYTO18,IL22,ILTIF,IL-TIF,IL-10-related T-cell-derived-inducible factor) is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3. 1. Brand, S. et al. (2007) American journal of physiology. Gastrointestinal and liver physiology 292, G1019-28. PMID: 17204547 2. Xie, MH. et al. (2000) The Journal of biological chemistry 275, 31335-9. PMID: 10875937 3. Jones, BC. et al. (2008) Structure (London, England : 1993) 16, 1333-44. PMID: 18599299 4. Akil, H. et al. (2015) PloS one 10, e0119872. PMID: 25793261 5. Moniruzzaman, M. et al. (2019) International journal of molecular sciences 20. PMID: 31311100 | ||||||
| 참고사항 | For research use only. |
문의하기
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
