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Anti-Mouse CD11b/ITGAM Recombinant Antibody (ASD-141) (MY474013)

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사양:
  • 50ug
  • 100ug
  • 1mg
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  • 개요

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개요
카탈로그 번호MY474013
설명
Anti-Mouse CD11b/ITGAM Recombinant Antibody (ASD-141) (MY474013) is a mouse monoclonal antibody detecting CD11b/ITGAM in ELISA. Suitable for Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
종 반응성Mouse
응용 분야ELISA
숙주 종Mouse
클론성Monoclonal
이소타입IgG1, kappa
클론 IDASD-141
타겟 CD11 antigen-like family member B, CD11b, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Integrin alpha-M, Itgam, Leukocyte adhesion receptor MO1
내독소 수준 < 10 EU/mg as determined by LAL method.
순도 >95% as determined by SDS-PAGE.
정제 Protein A/G purified from cell culture supernatant.
등록번호 P05555
형태 Liquid
저장 완충액 0.01M PBS pH 7.4

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

1. Losse, J. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 912-21. PMID: 20008295
2. DiScipio, RG. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 160, 4057-66. PMID: 9558116
3. Bai, M. et al. (2017) Blood 130, 2092-2100. PMID: 28807980
4. Jerke, U. et al. (2011) The Journal of biological chemistry 286, 7070-81. PMID: 21193407
5. Diamond, MS. et al. (1990) The Journal of cell biology 111, 3129-39. PMID: 1980124
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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