

| 카탈로그 번호 | MY474013 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Mouse CD11b/ITGAM Recombinant Antibody (ASD-141) (MY474013) is a mouse monoclonal antibody detecting CD11b/ITGAM in ELISA. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse | ||||
| 응용 분야 | ELISA | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1, kappa | ||||
| 클론 ID | ASD-141 | ||||
| 타겟 | CD11 antigen-like family member B, CD11b, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Integrin alpha-M, Itgam, Leukocyte adhesion receptor MO1 | ||||
| 내독소 수준 | < 10 EU/mg as determined by LAL method. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P05555 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Integrin alpha-M (CD11b/ITGAM) is a ~127 kDa protein. Integrin ITGAM/ITGB2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin ITGAM/ITGB2 is also a receptor for fibrinogen and factor X. It recognizes P1 and P2 peptides of fibrinogen gamma chain. 1. Losse, J. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 184, 912-21. PMID: 20008295 2. DiScipio, RG. et al. (1998) Journal of immunology (Baltimore, Md. : 1950) 160, 4057-66. PMID: 9558116 3. Bai, M. et al. (2017) Blood 130, 2092-2100. PMID: 28807980 4. Jerke, U. et al. (2011) The Journal of biological chemistry 286, 7070-81. PMID: 21193407 5. Diamond, MS. et al. (1990) The Journal of cell biology 111, 3129-39. PMID: 1980124 | ||||
| 참고사항 | For research use only. |
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