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| 카탈로그 번호 | HW664056 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-Human EMMPRIN/CD147 Reference Antibody (Metuzumab, RUO) (HW664056) is a monoclonal antibody detecting EMMPRIN/CD147.
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| 종 반응성 | Human | ||||
| 응용 분야 | ELISA, FCM, Functional assay | ||||
| 클론성 | Monoclonal | ||||
| 발현 시스템 | Mammalian cells | ||||
| 성질 | Recombinant | ||||
| 타겟 | 5F7, BSG, Basigin, CD147, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, HAb18G, Hepatoma-associated antigen, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor | ||||
| 내독소 수준 | < 10 EU/mg as determined by LAL method. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt.. | ||||
| 배경 | Basigin (CD147/BSG) is a ~42 kDa protein. Essential for normal retinal maturation and development. Acts as a retinal cell surface receptor for NXNL1 and plays an important role in NXNL1-mediated survival of retinal cone photoreceptors. In association with glucose transporter SLC16A1/GLUT1 and NXNL1, promotes retinal cone survival by enhancing aerobic glycolysis and accelerating the entry of glucose into photoreceptors. May act as a potent stimulator of IL6 secretion in multiple cell lines that include monocytes. 1. Aït-Ali, N. et al. (2015) Cell 161, 817-32. PMID: 25957687 2. Redzic, JS. et al. (2011) Journal of molecular biology 411, 68-82. PMID: 21620857 | ||||
| 참고사항 | For research use only. Not suitable for clinical or therapeutic use. |
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