Anti-Human ABCA1 Polyclonal Antibody (HF602014)

Name: Anti-Human ABCA1 Polyclonal Antibody
Brand: abinScience
SKU: HF602014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HF602014

설명

Anti-ABCA1 Polyclonal Antibody (HF602014) is a rabbit polyclonal antibody detecting ABCA1 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ABCA1 (Ser45-Glu271).

타겟

ATP-binding cassette transporter 1, ATP-binding cassette sub-family A member 1, Phospholipid-transporting ATPase ABCA1, ABC-1, ABCA1, ATP-binding cassette 1, Cholesterol efflux regulatory protein, ABC1, CERP

정제

Purified by antigen affinity column.

등록번호

O95477

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Phospholipid-transporting ATPase ABCA1 is a ~254 kDa protein. Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP. Thereby, participates in phospholipid transfer to apolipoproteins to form nascent high density lipoproteins/HDLs. Transports preferentially phosphatidylcholine over phosphatidylserine. May play a similar role in the efflux of intracellular cholesterol to apolipoproteins and the formation of nascent high density lipoproteins/HDLs. Translocates phospholipids from the outer face of the plasma membrane and forces it through its gateway and annulus into an elongated hydrophobic tunnel in its extracellular domain.

1. Quazi, F. et al. (2013) The Journal of biological chemistry 288, 34414-26. PMID: 24097981

2. Segrest, JP. et al. (2022) Nature communications 13, 4812. PMID: 35974019

3. Krimbou, L. et al. (2004) Journal of lipid research 45, 839-48. PMID: 14754908

4. Marcil, M. et al. (1999) Lancet (London, England) 354, 1341-6. PMID: 10533863

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-Human ABCA1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Human ABCA1 Polyclonal Antibody (HF602014)

개요

이미지

참고 문헌

데이터시트

SDS