Anti-Human ABCA1 Recombinant Antibody (SAA1535) (HF602013)

Name: Anti-Human ABCA1 Recombinant Antibody (SAA1535)
Brand: abinScience
SKU: HF602013
Price: 196 USD
Availability: InStock

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100ug
1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HF602013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1535

Clonality

Monoclonal

Target

ATP-binding cassette transporter 1, ATP-binding cassette sub-family A member 1, Phospholipid-transporting ATPase ABCA1, ABC-1, ABCA1, ATP-binding cassette 1, Cholesterol efflux regulatory protein, ABC1, CERP

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O95477

RRID

Anti-Human ABCA1 Antibody (SAA1535) (abinScience Cat# HF602013, RRID:AB_3727296)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Phospholipid-transporting ATPase ABCA1 is a ~254 kDa protein. Catalyzes the translocation of specific phospholipids from the cytoplasmic to the extracellular/lumenal leaflet of membrane coupled to the hydrolysis of ATP. Thereby, participates in phospholipid transfer to apolipoproteins to form nascent high density lipoproteins/HDLs. Transports preferentially phosphatidylcholine over phosphatidylserine. May play a similar role in the efflux of intracellular cholesterol to apolipoproteins and the formation of nascent high density lipoproteins/HDLs. Translocates phospholipids from the outer face of the plasma membrane and forces it through its gateway and annulus into an elongated hydrophobic tunnel in its extracellular domain.

1. Quazi, F. et al. (2013) The Journal of biological chemistry 288, 34414-26. PMID: 24097981

2. Segrest, JP. et al. (2022) Nature communications 13, 4812. PMID: 35974019

3. Krimbou, L. et al. (2004) Journal of lipid research 45, 839-48. PMID: 14754908

4. Marcil, M. et al. (1999) Lancet (London, England) 354, 1341-6. PMID: 10533863

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human ABCA1 Antibody (SAA1535)

References

Datasheet

Anti-Human ABCA1 Recombinant Antibody (SAA1535).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human ABCA1 Recombinant Antibody (SAA1535) (HF602013)

Overview

Images

References

Datasheet

SDS

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