Anti-ABCA3 Polyclonal Antibody (HV604014)

Name: Anti-ABCA3 Polyclonal Antibody
Brand: abinScience
SKU: HV604014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HV604014

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ABCA3 (Asp1358-Phe1635).

타겟

ABCA3, ATP-binding cassette sub-family A member 3, Phospholipid-transporting ATPase ABCA3, ABC3, ATP-binding cassette 3, ATP-binding cassette transporter 3, ABC-C transporter, Xenobiotic-transporting ATPase ABCA3

정제

Purified by antigen affinity column.

등록번호

Q99758

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Phospholipid-transporting ATPase ABCA3 is a ~191 kDa protein. Catalyzes the ATP-dependent transport of phospholipids such as phosphatidylcholine and phosphoglycerol from the cytoplasm into the lumen side of lamellar bodies, in turn participates in the lamellar bodies biogenesis and homeostasis of pulmonary surfactant. Transports preferentially phosphatidylcholine containing short acyl chains. In addition plays a role as an efflux transporter of miltefosine across macrophage membranes and free cholesterol (FC) through intralumenal vesicles by removing FC from the cell as a component of surfactant and protects cells from free cholesterol toxicity.

1. Matsumura, Y. et al. (2006) The Journal of biological chemistry 281, 34503-14. PMID: 16959783

2. Matsumura, Y. et al. (2007) FEBS letters 581, 3139-44. PMID: 17574245

3. Wittmann, T. et al. (2016) Pediatric pulmonology 51, 1284-1294. PMID: 27177387

4. Höppner, S. et al. (2017) Biochimica et biophysica acta. Molecular cell research 1864, 2330-2335. PMID: 28887056

5. Li, Y. et al. (2019) Biochimica et biophysica acta. Molecular and cell biology of lipids 1864, 158516. PMID: 31473345

6. Zarbock, R. et al. (2015) Biochimica et biophysica acta 1851, 987-95. PMID: 25817392

7. Dohmen, LC. et al. (2016) The Journal of biological chemistry 291, 9638-47. PMID: 26903515

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-ABCA3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ABCA3 Polyclonal Antibody (HV604014)

개요

이미지

참고 문헌

데이터시트

SDS

빠른 접근

문의하기