Anti-ABCC4 Polyclonal Antibody (HT434014)

Name: Anti-ABCC4 Polyclonal Antibody
Brand: abinScience
SKU: HT434014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HT434014

설명

Anti-ABCC4 Polyclonal Antibody (HT434014) is a rabbit polyclonal antibody detecting ABCC4 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ABCC4 (Ile1041-Gln1274).

타겟

MOAT-B, MOATB, Multi-specific organic anion transporter B, ATP-binding cassette sub-family C member 4, Multidrug resistance-associated protein 4, MRP4, ABCC4, MRP/cMOAT-related ABC transporter

정제

Purified by antigen affinity column.

등록번호

O15439

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

ATP-binding cassette sub-family C member 4 (ABCC4) is a ~149 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4) too. The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH).

1. van Aubel, RAMH. et al. (2002) Journal of the American Society of Nephrology : JASN 13, 595-603. PMID: 11856762

2. Zelcer, N. et al. (2003) The Biochemical journal 371, 361-7. PMID: 12523936

3. Sauna, ZE. et al. (2004) The Journal of biological chemistry 279, 48855-64. PMID: 15364914

4. Zhu, Y. et al. (2024) FEBS letters 598, 1967-1980. PMID: 38886124

5. Xie, Z. et al. (2025) Cell reports 44, 115466. PMID: 40138312

6. Reid, G. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 9244-9. PMID: 12835412

7. Rius, M. et al. (2003) Hepatology (Baltimore, Md.) 38, 374-84. PMID: 12883481

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-ABCC4 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ABCC4 Polyclonal Antibody (HT434014)

개요

이미지

참고 문헌

데이터시트

SDS