Anti-ABCD4 Polyclonal Antibody (HT035014)

Name: Anti-ABCD4 Polyclonal Antibody
Brand: abinScience
SKU: HT035014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HT035014

설명

Anti-ABCD4 Polyclonal Antibody (HT035014) is a rabbit polyclonal antibody detecting ABCD4 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ABCD4 (Leu356-Glu606).

타겟

ATP-binding cassette sub-family D member 4, ABCD4, PXMP1-L, PMP70-related protein, Peroxisomal membrane protein 1-like, P70R, PMP69, Peroxisomal membrane protein 69, PXMP1L, Lysosomal cobalamin transporter ABCD4

정제

Purified by antigen affinity column.

등록번호

O14678

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Lysosomal cobalamin transporter ABCD4 is a ~68 kDa protein. Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner. Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane. Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane.

1. Coelho, D. et al. (2012) Nature genetics 44, 1152-5. PMID: 22922874

2. Fettelschoss, V. et al. (2017) The Journal of biological chemistry 292, 11980-11991. PMID: 28572511

3. Xu, D. et al. (2019) Cell research 29, 1039-1041. PMID: 31467407

4. Kitai, K. et al. (2021) The Journal of biological chemistry 296, 100654. PMID: 33845046

5. Kawaguchi, K. et al. (2016) Scientific reports 6, 30183. PMID: 27456980

6. Deme, JC. et al. (2014) Molecular membrane biology 31, 250-61. PMID: 25535791

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-ABCD4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ABCD4 Polyclonal Antibody (HT035014)

개요

이미지

참고 문헌

데이터시트

SDS