Anti-ANP32A Polyclonal Antibody (HW663014)

Name: Anti-ANP32A Polyclonal Antibody
Brand: abinScience
SKU: HW663014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HW663014

설명

Anti-ANP32A Polyclonal Antibody (HW663014) is a rabbit polyclonal antibody detecting ANP32A in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ANP32A (Glu2-Asp175).

타겟

pp32, Putative HLA-DR-associated protein I, MAPM, ANP32A, C15orf1, Acidic leucine-rich nuclear phosphoprotein 32 family member A, Mapmodulin, LANP, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, PHAPI, Leucine-rich acidic nuclear protein, Acidic nuclear phosphoprotein pp32, PHAP1

정제

Purified by antigen affinity column.

등록번호

P39687

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) is a ~28 kDa protein. Multifunctional protein that is involved in the regulation of many processes including tumor suppression, apoptosis, cell cycle progression or transcription. Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation. In addition, plays a role in the modulation of histone acetylation and transcription as part of the INHAT (inhibitor of histone acetyltransferases) complex. Inhibits the histone-acetyltranferase activity of EP300/CREBBP (CREB-binding protein) and EP300/CREBBP-associated factor by histone masking. Preferentially binds to unmodified histone H3 and sterically inhibiting its acetylation and phosphorylation leading to cell growth inhibition.

1. Brody, JR. et al. (1999) The Journal of biological chemistry 274, 20053-5. PMID: 10400610

2. Bai, J. et al. (2001) Oncogene 20, 2153-60. PMID: 11360199

3. Fan, Z. et al. (2006) Cell death and differentiation 13, 1485-94. PMID: 16341127

4. Kim, HE. et al. (2008) Molecular cell 30, 239-47. PMID: 18439902

5. Seo, SB. et al. (2002) The Journal of biological chemistry 277, 14005-10. PMID: 11830591

6. Mazroui, R. et al. (2008) The Journal of cell biology 180, 113-27. PMID: 18180367

7. Tsujio, I. et al. (2005) FEBS letters 579, 363-72. PMID: 15642345

8. Cvetanovic, M. et al. (2007) EMBO reports 8, 671-7. PMID: 17557114

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-ANP32A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ANP32A Polyclonal Antibody (HW663014)

개요

이미지

참고 문헌

데이터시트

SDS

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